Pengarang: Robert L. Bronaugh
Edisi: 2
ISBN/ISSN: 978-0-8247-0626-5
Penerbit: Marcel Dekker, Inc.
Tahun Terbit: 2002
Tempat Terbit: New York
Bahasa: English
No. Panggil: TOP
GMD: Electronic Resource
This book is based on Bronaugh and Maibach’s Percutaneous Absorption: Third
Edition and In Vitro Percutaneous Absorption (Marcel Dekker, Inc.). It is a con-
densed entry into this complex area geared toward dermatologists, pharmacists,
toxicologists, cosmetic chemists working in the area of transdermal drug absorp-
tion, and others concerned with clinical treatment and studies involving the skin.
The chapters are divided into three parts. “Mechanisms of Absorption” contains
chapters that discuss the effects of skin metabolism, hair follicles, occlusion, and
other factors on skin absorption. Chapters in the “Methodology” part discuss the
various issues involved in measuring percutaneous absorption such as in vivo and
in vitro methodology, single versus multiple dosing, the relationship of blood flow
to absorption, and the significance of drug concentrations in the different layers of
skin. In “Drug and Cosmetic Absorption,” many updated and new chapters have
been added on topical dermatological products.
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