Detail E-Book
Oral Drug Absorption: prediction and assessment
Pengarang: Jennifer Dressman
Edisi: -
ISBN/ISSN: 0-8247-0272-7
Penerbit: Marcel Dekker, Inc.
Tahun Terbit: 2000
Tempat Terbit: New York
Judul Seri: Oral Drug Absorption: prediction and assessment
Bahasa: English
No. Panggil: ORA
GMD: Electronic Resource
Catatan
Oral Drug Absorption: Prediction and Assessment, edited by Jennifer B. Dressman and Hans Lennernäs, is a comprehensive scientific reference book that discusses the factors influencing drug absorption following oral administration. The book focuses on the processes involved in drug release from dosage forms and the subsequent passage of drugs across the gastrointestinal wall. It explores gastrointestinal physiology and pathophysiology, including gastrointestinal transit, intestinal permeability, and the effects of gastrointestinal diseases on drug absorption. Furthermore, the book examines various methods for assessing membrane permeability, such as theoretical predictions, in vitro techniques, animal perfusion studies, and human perfusion studies. It also discusses the effects of drug solubility and dissolution on oral bioavailability, including dissolution testing for immediate-release and extended-release dosage forms. In addition, the book presents in vitro–in vivo correlation (IVIVC) approaches, including convolution and deconvolution methods, to evaluate and predict drug performance in the human body. Overall, this book provides valuable scientific information for students, researchers, pharmacists, and pharmaceutical professionals involved in drug formulation, biopharmaceutics, pharmacokinetics, and the development of oral drug delivery systems.
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